Gpam - glycerol-3-phosphate acyltransferase, mitochondrial Gene

Rattus norvegicus

Gene ID: 29653 | Gene type: protein coding

About Gpam

Summary

Enables glycerol-3-phosphate O-acyltransferase activity. Involved in several processes, including glycerolipid biosynthetic process; positive regulation of triglyceride biosynthetic process; and response to fructose. Located in mitochondrial outer membrane. Biomarker of nephrotic syndrome and obesity. Orthologous to human GPAM (glycerol-3-phosphate Acyltransferase, mitochondrial). [provided by Alliance of Genome Resources, Apr 2022]

Gpam Products(1)

mRNA	Protein	Name
NM_017274.1	NP_058970.1	glycerol-3-phosphate acyltransferase 1, mitochondrial

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables glycerol-3-phosphate O-acyltransferase activity	IDA IDA: Inferred from direct assay	10446428	RGD
enables glycerol-3-phosphate O-acyltransferase activity	IMP IMP: Inferred from mutant phenotype	22905194	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to insulin stimulus	IDA IDA: Inferred from direct assay	18167308	RGD
involved in diacylglycerol biosynthetic process	IMP IMP: Inferred from mutant phenotype	22905194	RGD
involved in phosphatidic acid biosynthetic process	IMP IMP: Inferred from mutant phenotype	22905194	RGD
involved in positive regulation of triglyceride biosynthetic process	IDA IDA: Inferred from direct assay	15598672	RGD
involved in response to activity	IDA IDA: Inferred from direct assay	16234267	RGD
involved in response to cadmium ion	IEP IEP: Inferred from expression pattern	17066326	RGD
involved in response to fructose	IEP IEP: Inferred from expression pattern	19053045	RGD
involved in response to nutrient	IEP IEP: Inferred from expression pattern	26394137	RGD
involved in response to nutrient levels	IEP IEP: Inferred from expression pattern	18493788	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in mitochondrial membrane	IDA IDA: Inferred from direct assay	18167308	RGD
located in mitochondrial outer membrane	IDA IDA: Inferred from direct assay	17493869	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

glycerol-3-phosphate acyltransferase 1, mitochondrial

GPAT

GPAT-1

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05615	GPAM Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS20747	Gpam Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS27259	Gpam Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Gpam	NCBI	NCBI:57678

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