Zmynd8 - zinc finger, MYND-type containing 8 Gene

Rattus norvegicus

Also known as spikar; Prkcbp1

Gene ID: 296374 | Gene type: protein coding

About Zmynd8

Summary

Enables protein N-terminus binding activity. Involved in several processes, including positive regulation of dendritic spine development; positive regulation of filopodium assembly; and regulation of postsynapse organization. Located in cytoplasm; dendrite; and nucleus. Orthologous to human ZMYND8 (zinc finger MYND-type containing 8). [provided by Alliance of Genome Resources, Apr 2022]

Zmynd8 Products(1)

mRNA	Protein	Name
NM_001100838.1	NP_001094308.1	protein kinase C-binding protein 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	24117785	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in modulation of excitatory postsynaptic potential	IMP IMP: Inferred from mutant phenotype	24117785	RGD
involved in positive regulation of dendritic spine development	IMP IMP: Inferred from mutant phenotype	24117785	RGD
involved in positive regulation of dendritic spine maintenance	IMP IMP: Inferred from mutant phenotype	24117785	RGD
involved in positive regulation of filopodium assembly	IMP IMP: Inferred from mutant phenotype	24117785	RGD
involved in regulation of postsynaptic density protein 95 clustering	IMP IMP: Inferred from mutant phenotype	24117785	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in dendritic shaft	IDA IDA: Inferred from direct assay	24117785	RGD
located in dendritic spine	IDA IDA: Inferred from direct assay	24117785	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

protein kinase C-binding protein 1

spikar delta C

Zmynd8 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Zmynd8	A8C4G9	Dbn1	Rattus norvegicus	Q07266	Pull Down	24117785
Intra	Zmynd8	A8C4G9	Dbn1	Rattus norvegicus	Q07266	IF	24117785
Intra	Zmynd8	A8C4G9	Dbn1	Rattus norvegicus	Q07266	Y2H	24117785

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-403538	iZMYND8-34	Inhibitor	≥98.0%	Unkown
HY-RS16096	ZMYND8 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS20619	Zmynd8 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS27127	Zmynd8 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Zmynd8	NCBI	NCBI:23613

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