SLC39A8 - Slc39a8 solute carrier family 39 member 8 Gene

Rattus norvegicus

Gene ID: 295455 | Gene type: protein coding

About SLC39A8

Summary

Enables transition metal ion transmembrane transporter activity. Involved in inorganic cation transmembrane transport. Located in plasma membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIn. Orthologous to human SLC39A8 (solute carrier family 39 member 8). [provided by Alliance of Genome Resources, Apr 2022]

SLC39A8 Products(1)

mRNA	Protein	Name
NM_001011952.1	NP_001011952.1	metal cation symporter ZIP8 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables monoatomic cation:bicarbonate symporter activity	IDA IDA: Inferred from direct assay	22898811	RGD
enables zinc:bicarbonate symporter activity	IDA IDA: Inferred from direct assay	22898811	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cadmium ion transmembrane transport	IDA IDA: Inferred from direct assay	22898811	RGD
involved in cobalt ion transport	IDA IDA: Inferred from direct assay	22898811	RGD
involved in iron ion import across plasma membrane	IDA IDA: Inferred from direct assay	22898811	RGD
involved in manganese ion transmembrane transport	IDA IDA: Inferred from direct assay	22898811	RGD
involved in zinc ion import across plasma membrane	IDA IDA: Inferred from direct assay	22898811	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in plasma membrane	IDA IDA: Inferred from direct assay	22898811	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

metal cation symporter ZIP8

ZIP-8	solute carrier family 39 (metal ion transporter), member 8
solute carrier family 39 (zinc transporter), member 8	zinc transporter ZIP8
zrt- and Irt-like protein 8

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16232	Slc39a8 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS13239	SLC39A8 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS28561	Slc39a8 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	SLC39A8	NCBI	NCBI:64116

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