2. Gene
  3. Nipbl - NIPBL, cohesin loading factor Gene

Nipbl - NIPBL, cohesin loading factor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as IDN3

Gene ID: 294787 | Gene type: protein coding

About Nipbl

Summary

Predicted to enable several functions, including chromo shadow domain binding activity; histone deacetylase binding activity; and mediator complex binding activity. Predicted to be involved in several processes, including animal organ development; cellular response to X-ray; and sister chromatid cohesion. Predicted to act upstream of or within several processes, including embryonic viscerocranium morphogenesis; fat cell differentiation; and positive regulation of ossification. Predicted to be located in chromatin; cytosol; and nucleoplasm. Predicted to be part of Scc2-Scc4 cohesin loading complex and integrator complex. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 1. Orthologous to human NIPBL (NIPBL cohesin loading factor). [provided by Alliance of Genome Resources, Apr 2022]

Nipbl Products(4)

mRNA Protein Name
XM_039103540.1 XP_038959468.1 nipped-B-like protein isoform X3
XM_039103538.1 XP_038959466.1 nipped-B-like protein isoform X1
XM_039103539.1 XP_038959467.1 nipped-B-like protein isoform X2
XM_039103537.1 XP_038959465.1 nipped-B-like protein isoform X1
Protein Preferred Names Protein Names

nipped-B-like protein

Nipped-B homolog

delangin

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09305 NIPBL Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21000 Nipbl Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27517 Nipbl Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nipbl NCBI NCBI:25836