2. Gene
  3. Otub1 - OTU deubiquitinase, ubiquitin aldehyde binding 1 Gene

Otub1 - OTU deubiquitinase, ubiquitin aldehyde binding 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 293705 | Gene type: protein coding

About Otub1

Summary

Predicted to enable ubiquitin binding activity; ubiquitin protein Ligase binding activity; and ubiquitin-like protein-specific protease activity. Involved in cellular response to interleukin-1. Located in cytoplasm and nucleus. Orthologous to human OTUB1 (OTU Deubiquitinase, ubiquitin aldehyde binding 1). [provided by Alliance of Genome Resources, Apr 2022]

Otub1 Products(1)

mRNA Protein Name
NM_001106332.1 NP_001099802.1 ubiquitin thioesterase OTUB1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to interleukin-1 IEP
IEP: Inferred from expression pattern
22279542 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin thioesterase OTUB1

OTU domain, ubiquitin aldehyde binding 1

OTU domain-containing ubiquitin aldehyde-binding protein 1

deubiquitinating enzyme OTUB1

otubain-1

ubiquitin-specific-processing protease OTUB1

Related Agents

Pre-clinical Phase
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-151563 OTUB1/USP8-IN-1 Inhibitor 98.31% Unkown
HY-143345 EN523 Ligand 99.22% Unkown
HY-115878 NJH-2-057 Modulator 98.87% Unkown
HY-151563A OTUB1/USP8-IN-1 TFA Inhibitor 99.56% Unkown
HY-144999 LEB-03-146 98.08% Unkown
HY-143344 NJH-2-056 Modulator 98.23% Unkown
HY-143340 LEB-03-145 / Unkown
HY-143342 LEB-03-144 / Unkown
HY-143343 LEB-03-153 / Unkown
HY-RS09869 OTUB1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS16735 Otub1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23172 Otub1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Otub1 NCBI NCBI:55611