2. Membrane Transporter/Ion Channel
  3. CFTR
  4. NJH-2-057

NJH-2-057 is an EN523 OTUB1 recruiter linked to lumacaftor, a agent used to treat cystic fibrosis that binds ΔF508-CFTR.

For research use only. We do not sell to patients.

NJH-2-057

NJH-2-057 Chemical Structure

CAS No. : 2858812-70-9

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Solution
10 mM * 1 mL in DMSO In-stock
Solid
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Based on 1 publication(s) in Google Scholar

NJH-2-057 Related Antibodies

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Description

NJH-2-057 is an EN523 OTUB1 recruiter linked to lumacaftor, a agent used to treat cystic fibrosis that binds ΔF508-CFTR.

Molecular Weight

810.84

Formula

C43H44F2N6O8
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N1CC(N(CC1)C2=CC=C(CCC(NCCCCCNC(C3=CC=CC(C4=NC(NC(C5(CC5)C6=CC=C7OC(F)(OC7=C6)F)=O)=CC=C4C)=C3)=O)=O)O2)=O)C=C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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NJH-2-057 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NJH-2-0572858812-70-9CFTRCystic fibrosis transmembrane conductance regulatorInhibitorinhibitorinhibit

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HY-115878
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