2. Gene
  3. BRSK2 - Brsk2 BR serine/threonine kinase 2 Gene

BRSK2 - Brsk2 BR serine/threonine kinase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 293631 | Gene type: protein coding

About BRSK2

Summary

Enables protein serine/threonine kinase activity. Predicted to be involved in several processes, including cellular protein metabolic process; Cytoskeleton organization; and intracellular signal transduction. Predicted to act upstream of or within neuron projection morphogenesis and peptidyl-serine phosphorylation. Located in distal axon. Orthologous to human BRSK2 (BR serine/threonine kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

BRSK2 Products(16)

mRNA Protein Name
XM_039101272.1 XP_038957200.1 serine/threonine-protein kinase BRSK2 isoform X1
XM_039101275.1 XP_038957203.1 serine/threonine-protein kinase BRSK2 isoform X4
XM_039101273.1 XP_038957201.1 serine/threonine-protein kinase BRSK2 isoform X2
XM_039101274.1 XP_038957202.1 serine/threonine-protein kinase BRSK2 isoform X3
XM_039101277.1 XP_038957205.1 serine/threonine-protein kinase BRSK2 isoform X6
XM_039101276.1 XP_038957204.1 serine/threonine-protein kinase BRSK2 isoform X5
XM_039101281.1 XP_038957209.1 serine/threonine-protein kinase BRSK2 isoform X8
XM_039101285.1 XP_038957213.1 serine/threonine-protein kinase BRSK2 isoform X12
XM_039101279.1 XP_038957207.1 serine/threonine-protein kinase BRSK2 isoform X7
XM_039101284.1 XP_038957212.1 serine/threonine-protein kinase BRSK2 isoform X11
XM_039101278.1 XP_038957206.1 serine/threonine-protein kinase BRSK2 isoform X7
XM_039101280.1 XP_038957208.1 serine/threonine-protein kinase BRSK2 isoform X7
XM_039101286.1 XP_038957214.1 serine/threonine-protein kinase BRSK2 isoform X13
XM_039101283.1 XP_038957211.1 serine/threonine-protein kinase BRSK2 isoform X10
XM_039101282.1 XP_038957210.1 serine/threonine-protein kinase BRSK2 isoform X9
XM_039101287.1 XP_038957215.1 serine/threonine-protein kinase BRSK2 isoform X14
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein serine/threonine kinase activity IMP
IMP: Inferred from mutant phenotype
25788287 RGD
Cellular Component GO Annotation Evidence Reference Source
located in distal axon IMP
IMP: Inferred from mutant phenotype
25788287 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein kinase BRSK2

BR serine/threonine-protein kinase 2

brain serine/threonine kinase 2

brain-specific serine/threonine-protein kinase 2

serine/threonine-protein kinase BRSK2-like

serine/threonine-protein kinase SAD-A

Related Agents

Clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Phase
HY-18174 Prexasertib 98.74% Phase 2
HY-18174A Prexasertib dihydrochloride 99.41% Phase 2
HY-18174E Prexasertib dimesylate 98.90% Phase 2
HY-18174B Prexasertib Mesylate Hydrate / Phase 2
HY-18174C Prexasertib mesylate / Phase 2
Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01638 BRSK2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-18174H Prexasertib lactate / Unkown
HY-RS17337 Brsk2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23792 Brsk2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens BRSK2 NCBI NCBI:9024