2. Gene
  3. Zfp36l1 - zinc finger protein 36, C3H type-like 1 Gene

Zfp36l1 - zinc finger protein 36, C3H type-like 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Brf1; ERF1; cMG1; Berg36; TIS11b

Gene ID: 29344 | Gene type: protein coding

About Zfp36l1

Summary

Enables mRNA 3'-UTR AU-rich region binding activity. Involved in nuclear-transcribed mRNA catabolic process, deadenylation-independent decay and positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. Acts upstream of or within mRNA catabolic process. Located in cytosol. Orthologous to human ZFP36L1 (ZFP36 ring finger protein like 1). [provided by Alliance of Genome Resources, Apr 2022]

Zfp36l1 Products(1)

mRNA Protein Name
NM_017172.2 NP_058868.1 mRNA decay activator protein ZFP36L1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables mRNA 3'-UTR AU-rich region binding IDA
IDA: Inferred from direct assay
12748283 RGD
enables mRNA 3'-UTR AU-rich region binding IMP
IMP: Inferred from mutant phenotype
10751406 RGD
enables mRNA binding IDA
IDA: Inferred from direct assay
10751406 RGD
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within mRNA catabolic process IDA
IDA: Inferred from direct assay
10751406 RGD
involved in nuclear-transcribed mRNA catabolic process, deadenylation-independent decay IDA
IDA: Inferred from direct assay
11279239 RGD
involved in positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IDA
IDA: Inferred from direct assay
12748283 RGD
involved in regulation of mRNA stability IDA
IDA: Inferred from direct assay
11279239 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cytosol IDA
IDA: Inferred from direct assay
10751406 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mRNA decay activator protein ZFP36L1

EGF-inducible protein CMG1

TPA-induced sequence 11b

ZFP36-like 1

butyrate response factor 1

zinc finger protein 36, C3H1 type-like 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS16041 ZFP36L1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21270 Zfp36l1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27788 Zfp36l1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Zfp36l1 NCBI NCBI:677