2. Gene
  3. Ddt - D-dopachrome tautomerase Gene

Ddt - D-dopachrome tautomerase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 29318 | Gene type: protein coding

About Ddt

Summary

Predicted to enable cytokine receptor binding activity; phenylpyruvate tautomerase activity; and protease binding activity. Predicted to be involved in several processes, including negative regulation of macrophage chemotaxis; positive regulation of ERK1 and ERK2 cascade; and positive regulation of tumor necrosis factor production. Predicted to be located in cytoplasm. Predicted to be active in extracellular space. Orthologous to human DDT (D-dopachrome tautomerase) and DDTL (D-dopachrome tautomerase like). [provided by Alliance of Genome Resources, Apr 2022]

Ddt Products(1)

mRNA Protein Name
NM_024131.2 NP_077045.1 D-dopachrome decarboxylase
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables D-dopachrome decarboxylase activity IDA
IDA: Inferred from direct assay
8267597 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

D-dopachrome decarboxylase

dopachrome isomerase

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13690 Mitotane Inducer 99.94% Yes
HY-13690R Mitotane (Standard) Inducer / Unkown
Pre-clinical Phase
Bioactive Molecules (19)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B1984 p,p'-DDD 99.71% Unkown
HY-B1986 p,p'-DDE Antagonist 99.51% Unkown
HY-13690S1 Mitotane-13C6 98.62% Unkown
HY-B1873S Methoxychlor-d6 98.22% Unkown
HY-B1970S o,p'-DDT-d8 94.65% Unkown
HY-122551 Chlorfenethol / Unkown
HY-13690S2 Mitotane-d8 / Unkown
HY-13690S3 Mitotane-13C12 Inducer / Unkown
HY-159086 RGB097 Inhibitor / Unkown
HY-159087 RGB110 / Unkown
HY-B1984S p,p'-DDD-d8 / Unkown
HY-B1986S p,p'-DDE-d8 / Unkown
HY-RS03627 DDT Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-121779 o,p'-DDE / Unkown
HY-B1970 o,p'-DDT / Unkown
HY-RS17792 Ddt Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24260 Ddt Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W750297 p,p'-DDD-13C12 / Unkown
HY-W753141 p,p'-DDE-13C12 Antagonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ddt NCBI NCBI:1652
Canis familiaris Ddt NCBI NCBI:100856501
Macaca fascicularis Ddt NCBI NCBI:102140262
Mus musculus Ddt NCBI NCBI:13202