2. Gene
  3. Cbr1 - carbonyl reductase 1 Gene

Cbr1 - carbonyl reductase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Cbr; PG-9-KR

Gene ID: 29224 | Gene type: protein coding

About Cbr1

Summary

Enables carbonyl reductase (NADPH) activity. Involved in several processes, including ovulation from ovarian follicle; phylloquinone catabolic process; and prostaglandin catabolic process. Located in microvillus; nucleus; and plasma membrane. Biomarker of chronic kidney disease. Orthologous to human CBR1 (carbonyl reductase 1). [provided by Alliance of Genome Resources, Apr 2022]

Cbr1 Products(1)

mRNA Protein Name
NM_019170.2 NP_062043.1 carbonyl reductase [NADPH] 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables carbonyl reductase (NADPH) activity IDA
IDA: Inferred from direct assay
7705364 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
24882364 RGD
Biological Process GO Annotation Evidence Reference Source
involved in ovulation from ovarian follicle IEP
IEP: Inferred from expression pattern
10642578 RGD
involved in phylloquinone catabolic process IDA
IDA: Inferred from direct assay
16359670 RGD
involved in prostaglandin catabolic process IDA
IDA: Inferred from direct assay
7705364 RGD
involved in response to estradiol IDA
IDA: Inferred from direct assay
3796215 RGD
involved in response to gonadotropin IEP
IEP: Inferred from expression pattern
12444039 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
12399253 RGD
involved in response to progesterone IDA
IDA: Inferred from direct assay
3796215 RGD
involved in response to testosterone IEP
IEP: Inferred from expression pattern
16457595 RGD
involved in steroid catabolic process IDA
IDA: Inferred from direct assay
7705364 RGD
Cellular Component GO Annotation Evidence Reference Source
located in microvillus IDA
IDA: Inferred from direct assay
16457595 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

carbonyl reductase [NADPH] 1

15-hydroxyprostaglandin dehydrogenase

20-beta-hydroxysteroid dehydrogenase

Cbr 1

NADPH-dependent carbonyl reductase 1

alcohol dehydrogenase [NAD(P)+] CBR1

prostaglandin 9-ketoreductase

prostaglandin-E(2) 9-reductase

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N0148 Rutin 98.09% Unkown
Pre-clinical Phase
Bioactive Molecules (16)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13930 Miquelianin 99.96% Unkown
HY-N2609 7,4'-Dihydroxyflavone Inhibitor 99.68% Unkown
HY-156694 Hydroxy-PP-Me 99.92% Unkown
HY-155587 Hydroxy-PP Inhibitor 99.66% Unkown
HY-121710 MonoHER 97.02% Unkown
HY-157444 5,3',4',3'',4'',5''-6-O-Ethyl-EGCG Inhibitor / Unkown
HY-157445 CBR1-IN-3 / Unkown
HY-157447 CBR1-IN-4 / Unkown
HY-157448 CBR1-IN-6 Inducer / Unkown
HY-157449 CBR1-IN-5 / Unkown
HY-157450 YF-Mo1 Inhibitor / Unkown
HY-157451 CBR1-IN-7 / Unkown
HY-157452 (8S)-Methyl zearalenone Inhibitor / Unkown
HY-RS02004 CBR1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18341 Cbr1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24820 Cbr1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cbr1 NCBI NCBI:873