2. Gene
  3. Chka - choline kinase alpha Gene

Chka - choline kinase alpha Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Chk; CK-R

Gene ID: 29194 | Gene type: protein coding

About Chka

Summary

Enables ATP binding activity; choline binding activity; and phosphotransferase activity, alcohol group as acceptor. Involved in several processes, including choline metabolic process; ethanolamine metabolic process; and response to 3-methylcholanthrene. Predicted to be active in cytoplasm. Biomarker of colon Cancer and transient cerebral ischemia. Orthologous to human CHKA (Choline Kinase alpha). [provided by Alliance of Genome Resources, Apr 2022]

Chka Products(2)

mRNA Protein Name
NM_001398586.1 NP_001385515.1 choline kinase alpha isoform 1
NM_017127.3 NP_058823.1 choline kinase alpha isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables ATP binding IDA
IDA: Inferred from direct assay
12815193 RGD
enables choline binding IDA
IDA: Inferred from direct assay
12815193 RGD
enables choline kinase activity IDA
IDA: Inferred from direct assay
1577786 RGD
enables ethanolamine kinase activity IDA
IDA: Inferred from direct assay
1577786 RGD
Biological Process GO Annotation Evidence Reference Source
involved in choline metabolic process IDA
IDA: Inferred from direct assay
12815193 RGD
involved in ethanolamine metabolic process IDA
IDA: Inferred from direct assay
1577786 RGD
involved in response to 3-methylcholanthrene IEP
IEP: Inferred from expression pattern
7852267 RGD
involved in response to toxic substance IEP
IEP: Inferred from expression pattern
7852267 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

choline kinase alpha

CHETK-alpha

CK

EK

choline kinase R

ethanolamine kinase

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02633 CHKA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21311 Chka Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27830 Chka Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Chka NCBI NCBI:1119