2. Gene
  3. Aga - aspartylglucosaminidase Gene

Aga - aspartylglucosaminidase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 290923 | Gene type: protein coding

About Aga

Summary

Enables N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity and protein self-association. Predicted to be involved in protein deglycosylation. Located in lysosome. Human ortholog(s) of this gene implicated in aspartylglucosaminuria and lysosomal storage disease. Orthologous to human AGA (aspartylglucosaminidase). [provided by Alliance of Genome Resources, Apr 2022]

Aga Products(1)

mRNA Protein Name
NM_001031641.1 NP_001026811.1 N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase precursor
Protein Preferred Names Protein Names

N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase

N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase

glycosylasparaginase

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-132609 Patisiran sodium 99.09% Unkown
HY-108753 Eteplirsen 98.50% Unkown
Clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Phase
HY-143230 Custirsen 98.71% Phase 3
HY-132596 Tivanisiran Inhibitor 92.62% Phase 3
HY-147412 Ultevursen / Phase 3
HY-150724 ODN 1018 Agonist 96.23% Phase 2
HY-145726 ISIS 104838 Inhibitor / Phase 2
Pre-clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P1851A AGA-(C8R) HNG17, humanin derivative TFA 98.34% Unkown
HY-118528A TP0427736 hydrochloride Inhibitor 99.22% Unkown
HY-161618 MJ04 Inhibitor 98.08% Unkown
HY-170448 PROTAC AR Degrader-9 Degrader / Unkown
HY-170450 AR ligand-38 Ligand / Unkown
HY-P1851 AGA-(C8R) HNG17, humanin derivative / Unkown
HY-RS00436 AGA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17521 Aga Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23977 Aga Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aga NCBI NCBI:175
Mus musculus Aga NCBI NCBI:11593