1. Gene
  2. Tfr2 - transferrin receptor 2 Gene

Tfr2 - transferrin receptor 2 Gene

Rattus norvegicus

Also known as Trfr2

Gene ID: 288562 | Gene type: protein coding

About Tfr2

Summary

Predicted to enable co-receptor binding activity and Transferrin Receptor activity. Involved in acute-phase response. Predicted to be located in cytoplasmic vesicle. Predicted to be integral component of plasma membrane. Predicted to be part of HFE-transferrin receptor complex. Predicted to be active in external side of plasma membrane. Used to study hemochromatosis type 3. Human ortholog(s) of this gene implicated in hemochromatosis and hemochromatosis type 3. Orthologous to human TFR2 (Transferrin Receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Tfr2 Products(1)

mRNA Protein Name
NM_001105916.1 NP_001099386.1 transferrin receptor protein 2
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in acute-phase response IEP
IEP: Inferred from expression pattern
21437659 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transferrin receptor protein 2

Orthologs Information

Species Symbol Source ID
Homo sapiens Tfr2 NCBI NCBI:7036
Mus musculus Tfr2 NCBI NCBI:50765