Spib - Spi-B transcription factor (Spi-1/PU.1 related) Gene

Mus musculus

Also known as Spi-B

Gene ID: 272382 | Gene type: protein coding

About Spib

Summary

Enables DNA-binding transcription factor activity. Involved in immature B cell differentiation. Acts upstream of or within macrophage differentiation and regulation of transcription, DNA-templated. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in brain and liver. Orthologous to human SPIB (Spi-B transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Spib Products(1)

mRNA	Protein	Name
NM_019866.1	NP_063919.1	transcription factor Spi-B

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA-binding transcription factor activity	IDA IDA: Inferred from direct assay	11980719	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in immature B cell differentiation	IGI IGI: Inferred from genetic interaction	28062693	MGI
acts upstream of or within macrophage differentiation	IDA IDA: Inferred from direct assay	11980719	MGI
acts upstream of or within regulation of DNA-templated transcription	IDA IDA: Inferred from direct assay	11980719	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

transcription factor Spi-B

Ets transcription factor Spi-B

Spi-1/PU.1 related

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13672	SPIB Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS22331	Spib Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Spib	NCBI	NCBI:6689

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