Etv3 - ets variant 3 Gene

Also known as Pe1; METS

About Etv3

Summary

Enables DEAD/H-box RNA helicase binding activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in cellular response to granulocyte macrophage colony-stimulating factor stimulus and negative regulation of cell population proliferation. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in chromatin. Part of RNA polymerase II transcription repressor complex. Is expressed in several structures, including central nervous system; dorsal root ganglion; early conceptus; genitourinary system; and retina. Orthologous to human ETV3 (ETS variant transcription factor 3). [provided by Alliance of Genome Resources, Apr 2022]