2. Gene
  3. Ahcy - S-adenosylhomocysteine hydrolase Gene

Ahcy - S-adenosylhomocysteine hydrolase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as CuBP; SAHH

Gene ID: 269378 | Gene type: protein coding

About Ahcy

Summary

Enables adenosylhomocysteinase activity; copper ion binding activity; and protein self-association. Acts upstream of or within S-adenosylhomocysteine catabolic process. Located in cytosol. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in hypermethioninemia with deficiency of S-adenosylhomocysteine hydrolase. Orthologous to human AHCY (adenosylhomocysteinase). [provided by Alliance of Genome Resources, Apr 2022]

Ahcy Products(1)

mRNA Protein Name
NM_016661.3 NP_057870.3 adenosylhomocysteinase
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables NAD binding IDA
IDA: Inferred from direct assay
7657650 MGI
enables adenosylhomocysteinase activity IDA
IDA: Inferred from direct assay
7657650 MGI
enables copper ion binding IDA
IDA: Inferred from direct assay
8419320 MGI
enables identical protein binding IPI
IPI: Inferred from physical interaction
8419320 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15102471 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within S-adenosylhomocysteine catabolic process IDA
IDA: Inferred from direct assay
12023972 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytosol IDA
IDA: Inferred from direct assay
8419320 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adenosylhomocysteinase

S-adenosyl-L-homocysteine hydrolase

adoHcyase

liver copper-binding protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12186 3-Deazaneplanocin A hydrochloride Inhibitor 99.98% Unkown
HY-10442 3-Deazaneplanocin A Inhibitor 99.97% Unkown
HY-112639 Aristeromycin Inhibitor 99.34% Unkown
HY-149048 Adenosylhomocysteinase / Unkown
HY-RS00476 AHCY Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16799 Ahcy Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23240 Ahcy Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ahcy NCBI NCBI:191