2. Gene
  3. Prrx1 - paired related homeobox 1 Gene

Prrx1 - paired related homeobox 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Pmx1; Prx-1

Gene ID: 266813 | Gene type: protein coding

About Prrx1

Summary

Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; HMG box domain binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in agnathia-otocephaly complex. Orthologous to human PRRX1 (paired related homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Prrx1 Products(2)

mRNA Protein Name
NM_153821.2 NP_722543.1 paired mesoderm homeobox protein 1
NM_153821.2 NP_722543.1 paired mesoderm homeobox protein 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
8749718 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

paired mesoderm homeobox protein 1

paired mesoderm homeobox 1

paired-related homeobox protein 1

rHox

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11243 PRRX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20468 Prrx1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26977 Prrx1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prrx1 NCBI NCBI:5396