2. Gene
  3. Nptx1 - neuronal pentraxin 1 Gene

Nptx1 - neuronal pentraxin 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 266777 | Gene type: protein coding

About Nptx1

Summary

Predicted to enable metal ion binding activity. Involved in several processes, including mitochondrial fragmentation involved in apoptotic process; neurotransmitter receptor localization to postsynaptic specialization membrane; and regulation of postsynaptic density assembly. Located in mitochondrion; neuron projection; and plasma membrane. Is active in glutamatergic synapse and synaptic cleft. Orthologous to human NPTX1 (neuronal pentraxin 1). [provided by Alliance of Genome Resources, Apr 2022]

Nptx1 Products(1)

mRNA Protein Name
NM_153735.4 NP_714957.1 neuronal pentraxin-1 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to glucose stimulus IEP
IEP: Inferred from expression pattern
22427704 RGD
involved in cellular response to potassium ion IDA
IDA: Inferred from direct assay
22279230 RGD
involved in mitochondrial fragmentation involved in apoptotic process IMP
IMP: Inferred from mutant phenotype
22279230 RGD
involved in mitochondrial transport IMP
IMP: Inferred from mutant phenotype
22279230 RGD
involved in neurotransmitter receptor localization to postsynaptic specialization membrane EXP
EXP: Inferred from Experiment
29024665 RGD
involved in neurotransmitter receptor localization to postsynaptic specialization membrane IDA
IDA: Inferred from direct assay
29024665 RGD
involved in neurotransmitter receptor localization to postsynaptic specialization membrane IMP
IMP: Inferred from mutant phenotype
29024665 RGD
involved in postsynaptic density assembly EXP
EXP: Inferred from Experiment
29024665 RGD
involved in postsynaptic density assembly IDA
IDA: Inferred from direct assay
29024665 RGD
involved in postsynaptic density assembly IMP
IMP: Inferred from mutant phenotype
29024665 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse EXP
EXP: Inferred from Experiment
29024665 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
29024665 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
29024665 RGD
is active in synaptic cleft IDA
IDA: Inferred from direct assay
29024665 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuronal pentraxin-1

47 kDa taipoxin-binding protein

NP-I

NP1

neuronal pentraxin I

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09505 NPTX1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19725 Nptx1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26221 Nptx1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nptx1 NCBI NCBI:4884