2. Gene
  3. Tor1a - torsin family 1, member A Gene

Tor1a - torsin family 1, member A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Dyt1

Gene ID: 266606 | Gene type: protein coding

About Tor1a

Summary

Enables Kinesin binding activity. Involved in response to oxidative stress. Located in cytoplasmic vesicle and growth cone. Human ortholog(s) of this gene implicated in arthrogryposis multiplex congenita-5 and torsion dystonia 1. Orthologous to human TOR1A (torsin family 1 member A). [provided by Alliance of Genome Resources, Apr 2022]

Tor1a Products(1)

mRNA Protein Name
NM_153303.2 NP_695215.2 torsin-1A precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables kinesin binding IDA
IDA: Inferred from direct assay
14970196 RGD
enables kinesin binding IPI
IPI: Inferred from physical interaction
14970196 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
21102408 RGD
Biological Process GO Annotation Evidence Reference Source
involved in response to oxidative stress IDA
IDA: Inferred from direct assay
12671990 RGD
Cellular Component GO Annotation Evidence Reference Source
located in growth cone IDA
IDA: Inferred from direct assay
14970196 RGD
located in secretory granule IDA
IDA: Inferred from direct assay
18167355 RGD
located in synaptic vesicle IDA
IDA: Inferred from direct assay
21102408 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

torsin-1A

dystonia 1 protein

dystonia 1, torsion (autosomal dominant

dystonia 1, torsion (autosomal dominant

torsin A)

torsin A

torsin ATPase 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14903 TOR1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22872 Tor1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29386 Tor1a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tor1a NCBI NCBI:1861