2. Gene
  3. Asns - asparagine synthetase (glutamine-hydrolyzing) Gene

Asns - asparagine synthetase (glutamine-hydrolyzing) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 25612 | Gene type: protein coding

About Asns

Summary

Enables asparagine synthase (glutamine-hydrolyzing) activity and identical protein binding activity. Involved in several processes, including asparagine biosynthetic process; cellular response to glucose starvation; and response to follicle-stimulating hormone. Predicted to be active in cytosol. Biomarker of hepatocellular carcinoma. Orthologous to human ASNS (asparagine synthetase (glutamine-hydrolyzing)). [provided by Alliance of Genome Resources, Apr 2022]

Asns Products(1)

mRNA Protein Name
NM_013079.2 NP_037211.2 asparagine synthetase [glutamine-hydrolyzing]
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables asparagine synthase (glutamine-hydrolyzing) activity IDA
IDA: Inferred from direct assay
6132621 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
6132621 RGD
Biological Process GO Annotation Evidence Reference Source
involved in amino acid metabolic process IEP
IEP: Inferred from expression pattern
7818476 RGD
involved in asparagine biosynthetic process IDA
IDA: Inferred from direct assay
2887559 RGD
involved in cellular response to glucose starvation IEP
IEP: Inferred from expression pattern
10085239 RGD
involved in cellular response to hormone stimulus IEP
IEP: Inferred from expression pattern
1543496 RGD
involved in liver development IEP
IEP: Inferred from expression pattern
237754 RGD
involved in response to aldosterone IEP
IEP: Inferred from expression pattern
29713904 RGD
involved in response to amino acid IEP
IEP: Inferred from expression pattern
9176161 RGD
involved in response to follicle-stimulating hormone IEP
IEP: Inferred from expression pattern
7915898 RGD
involved in response to light stimulus IEP
IEP: Inferred from expression pattern
16885923 RGD
involved in response to mechanical stimulus IEP
IEP: Inferred from expression pattern
16864689 RGD
involved in response to nutrient levels IEP
IEP: Inferred from expression pattern
6104809 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
6122150 RGD
involved in response to toxic substance IEP
IEP: Inferred from expression pattern
18164361 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

asparagine synthetase [glutamine-hydrolyzing]

glutamine-dependent asparagine synthetase

Related Agents

Approval
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N0667 L-Asparagine ≥98.0% Unkown
HY-14874 Topiroxostat Inhibitor 99.06% Unkown
HY-W017443 L-Asparagine monohydrate 99.77% Unkown
HY-123319 Antofloxacin hydrochloride Inhibitor / Unkown
HY-123319A Antofloxacin Inhibitor / Unkown
Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-103018 Gusacitinib Inhibitor 99.41% Phase 2
HY-103018A Gusacitinib hydrochloride Inhibitor / Phase 2
Pre-clinical Phase
Bioactive Molecules (100)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-128946 CL2A-SN-38 99.07% Unkown
HY-136579 ASN007 Inhibitor 99.70% Unkown
HY-128923 SKF-34288 hydrochloride Inhibitor 96.35% Unkown
HY-112205A RR-11a analog Inhibitor 99.12% Unkown
HY-136626 Z-Ala-Ala-Asn-AMC 99.43% Unkown
HY-108625 SHA 68 Antagonist 99.84% Unkown
HY-139147 iHCK-37 Inhibitor 99.52% Unkown
HY-W002327 Fmoc-Asn(Trt)-OH 99.96% Unkown
HY-114174 Fmoc-Ala-Glu-Asn-Lys-NH2 99.13% Unkown
HY-156586 Egalognastat Inhibitor 99.63% Unkown
HY-136579A ASN007 benzenesulfonate Inhibitor 99.72% Unkown
HY-P4385 (Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) Antagonist 99.32% Unkown
HY-P1043A NGR peptide Trifluoroacetate 98.89% Unkown
HY-128111 ASN02563583 Activator 99.21% Unkown
HY-111323 ASN06917370 99.23% Unkown
HY-164668 ADC Control Human IgG1-SN-38 96.24% Unkown
HY-N0667S5 L-Asparagine-d3 hydrate 99.64% Unkown
HY-N0667S2 L-Asparagine-15N2 monohydrate ≥98.0% Unkown
HY-N9446 H-Asn(glcnac-beta-D)-OH 98.65% Unkown
HY-W010378 D-Asparagine ≥98.0% Unkown
HY-W017443S L-Asparagine-13C4,15N2 monohydrate ≥98.0% Unkown
HY-113667 ASN04885796 Activator 99.61% Unkown
HY-150579 Keap1-Nrf2-IN-13 Inhibitor 96.77% Unkown
HY-B1803A Tracazolate hydrochloride Modulator 99.24% Unkown
HY-W009085 Fmoc-Asn-OH 99.17% Unkown
HY-125028 Hck-IN-1 Inhibitor 98.53% Unkown
HY-150242A Cbz-Ala-Ala-Asn TFA 99.54% Unkown
HY-162238 OSM-S-106 Inhibitor 99.34% Unkown
HY-128128 ASN04421891 Modulator 99.00% Unkown
HY-141464 Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH 95.03% Unkown
HY-148393 G0 N-glycan-Asn 99.95% Unkown
HY-E70068 Endo-β-N-acetylglucosaminidase (Endo S) / Unkown
HY-P1809A Velmupressin acetate Agonist 99.47% Unkown
HY-W017443S1 L-Asparagine-amide-15N monohydrate 99.80% Unkown
HY-129360A Ala-Ala-Asn-PAB TFA / Unkown
HY-N0667S L-Asparagine-13C4,15N2,d8 99% Unkown
HY-P10485 Glp-Asn-Pro-AMC 99.26% Unkown
HY-P3882 Fmoc-Ala-Glu-Gln-Lys-NH2 99.90% Unkown
HY-W008233 Z-Asn-OH 98.76% Unkown
HY-W010378R D-Asparagine (Standard) / Unkown
HY-W017443S2 L-Asparagine-13C4,15N2,d3 monohydrate 99.90% Unkown
HY-P1809 Velmupressin Agonist / Unkown
HY-P1810 c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-Agm Agonist / Unkown
HY-150787 BMS-986339 / Unkown
HY-P1043 NGR peptide / Unkown
HY-113761 ASN03576800 Inhibitor 99.61% Unkown
HY-122179 NUCC-555 Antagonist / Unkown
HY-128947 CL2 Linker / Unkown
HY-129360 Ala-Ala-Asn-PAB / Unkown
HY-129361 Fmoc-Ala-Ala-Asn-PABC-PNP / Unkown
HY-130933 Fmoc-Ala-Ala-Asn(Trt)-OH 99.80% Unkown
HY-131463 ASN-1377642 Antagonist / Unkown
HY-136733 Ac-DNLD-CHO Inhibitor / Unkown
HY-139245 MC-Ala-Ala-Asn-PAB / Unkown
HY-141149 Fmoc-PEG4-Ala-Ala-Asn-PAB / Unkown
HY-141150 Azido-PEG5-Ala-Ala-Asn-PAB / Unkown
HY-141151 Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB / Unkown
HY-144628 Fmoc-Asn-Pro-Val-PABC-PNP 99.34% Unkown
HY-144629 Asn-Pro-Val-PABC-MMAE TFA / Unkown
HY-144630 diSPhMC-Asn-Pro-Val-PABC-MMAE / Unkown
HY-148031 MC-Ala-Ala-Asn-PAB-PNP / Unkown
HY-148392 Neu5Gcα(2-6) N-Glycan-Asn / Unkown
HY-149360 P-gb-IN-1 Inhibitor / Unkown
HY-151146 (1R,3S)-THCCA-Asn Inhibitor / Unkown
HY-156314 ASN 07115873 Inhibitor / Unkown
HY-164457 ASN-001 Inhibitor / Unkown
HY-172472 DSPE-PEG1000-NGR / Unkown
HY-172473 DSPE-PEG2000-NGR / Unkown
HY-172474 DSPE-PEG5000-NGR / Unkown
HY-N0667S1 L-Asparagine-15N2,d8 / Unkown
HY-N0667S3 L-Asparagine-13C4 monohydrate / Unkown
HY-N0667S4 L-Asparagine-4-13C monohydrate / Unkown
HY-N0667S7 L-Asparagine-13C4,15N2 / Unkown
HY-N15365 Antcin B Inhibitor / Unkown
HY-P1610 Asudemotide Inducer / Unkown
HY-P1962 β-Secretase inhibitor Inhibitor / Unkown
HY-P2212 (Asn1,Val5)-Angiotensin II / Unkown
HY-P2397 Fmoc-Asn(Trt)-Thr(psi(Me,Me)pro)-OH / Unkown
HY-P2401 Fmoc-Asn(Trt)-Ser(psi(Me,Me)pro)-OH / Unkown
HY-P3220 [D-Asn5]-Oxytocin Activator / Unkown
HY-P3615 [Asn18] Endothelin-1, human Agonist / Unkown
HY-P3716 H(-Asn-Pro-Asn-Ala)2-OH / Unkown
HY-P4019 Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2 / Unkown
HY-P4407 (D-Asn28)-Exenatide Control / Unkown
HY-P4919 Mca-SEVNLDAEFK(Dnp) / Unkown
HY-P5415 DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS / Unkown
HY-RS01098 ASNS Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W017443S3 L-Asparagine-15N2,d3 monohydrate / Unkown
HY-W017443S4 L-Asparagine-1,2,3,4-13C4 monohydrate / Unkown
HY-W091365 Boc-Asn(Xan)-OH / Unkown
HY-118731 TNK-6123 Activator / Unkown
HY-131092 H-Asn-Arg-OH / Unkown
HY-141152 Azido-PEG4-Ala-Ala-Asn(Trt)-PAB / Unkown
HY-141153 Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB-PNP / Unkown
HY-148389 Disialo-Asn / Unkown
HY-151829 Fmoc-L-Asn(EDA-N3)-OH / Unkown
HY-157338 NHS-Ala-Ala-Asn-active metabolite Inhibitor / Unkown
HY-RS19117 Asns Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25607 Asns Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W002327S Fmoc-Asn(Trt)-OH-13C4,15N2 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Asns NCBI NCBI:440