2. Gene
  3. Lypla1 - lysophospholipase 1 Gene

Lypla1 - lysophospholipase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as 25KDL; Pla1a

Gene ID: 25514 | Gene type: protein coding

About Lypla1

Summary

Enables lysophospholipase activity. Predicted to be involved in protein depalmitoylation. Predicted to act upstream of or within negative regulation of Golgi to plasma membrane protein transport. Predicted to be located in several cellular components, including cytosol; endoplasmic reticulum; and nuclear membrane. Predicted to be active in cytoplasm. Orthologous to human LYPLA1 (lysophospholipase 1). [provided by Alliance of Genome Resources, Apr 2022]

Lypla1 Products(1)

mRNA Protein Name
NM_013006.2 NP_037138.1 acyl-protein thioesterase 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables lysophospholipase activity IDA
IDA: Inferred from direct assay
9644627 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acyl-protein thioesterase 1

APT-1

LPL-I

lysoPLA I

lysophospholipase I

palmitoyl-protein hydrolase

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100736 ML348 Inhibitor 99.97% Unkown
HY-128035 ML-211 Inhibitor 98.06% Unkown
HY-RS07921 LYPLA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17852 Lypla1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24321 Lypla1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lypla1 NCBI NCBI:10434