2. Gene
  3. Vps35 - VPS35 retromer complex component Gene

Vps35 - VPS35 retromer complex component Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Mem3

Gene ID: 25479 | Gene type: protein coding

About Vps35

Summary

Predicted to enable D1 Dopamine Receptor binding activity. Involved in retrograde transport, endosome to Golgi. Located in cytosol. Part of retromer complex. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 17. Orthologous to human VPS35 (VPS35 retromer complex component). [provided by Alliance of Genome Resources, Apr 2022]

Vps35 Products(1)

mRNA Protein Name
NM_001105718.2 NP_001099188.2 vacuolar protein sorting-associated protein 35
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in retrograde transport, endosome to Golgi IMP
IMP: Inferred from mutant phenotype
23395371 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cytosol IDA
IDA: Inferred from direct assay
11102511 RGD
part of retromer complex IDA
IDA: Inferred from direct assay
11102511 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vacuolar protein sorting-associated protein 35

Maternal embryonic message 3

vacuolar protein sorting 35 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15685 VPS35 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS15686 VPS35L Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21083 Vps35 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27600 Vps35 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vps35 NCBI NCBI:55737