2. Gene
  3. Cast - calpastatin Gene

Cast - calpastatin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 25403 | Gene type: protein coding

About Cast

Summary

Enables calcium-dependent cysteine-type endopeptidase inhibitor activity and protease binding activity. Involved in several processes, including animal organ development; egg activation; and myoblast fusion. Located in several cellular components, including cytoplasm; nucleus; and postsynaptic density. Used to study brain ischemia. Human ortholog(s) of this gene implicated in Parkinson's disease; autoimmune disease (multiple); congenital myasthenic syndrome 1A; and vasculitis. Orthologous to human CAST (calpastatin). [provided by Alliance of Genome Resources, Apr 2022]

Cast Products(3)

mRNA Protein Name
NM_001033715.1 NP_001028887.1 calpastatin isoform b
NM_001033716.1 NP_001028888.1 calpastatin isoform c
NM_053295.2 NP_445747.2 calpastatin isoform a
Protein Preferred Names Protein Names

calpastatin

calpain inhibitor

Cast Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Cast P27321 Capn2 Rattus norvegicus Q07009
SPR
17543955
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N10637 N-Acetyldopamine dimer-1 / Unkown
HY-N12703 N-Acetyldopamine dimmers A / Unkown
HY-RS01978 CAST Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04477 ERC2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17878 Cast Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24347 Cast Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cast NCBI NCBI:831
Mus musculus Cast NCBI NCBI:12380