2. Gene
  3. ATF3 - Atf3 activating transcription factor 3 Gene

ATF3 - Atf3 activating transcription factor 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as LRFI; LRF-1

Gene ID: 25389 | Gene type: protein coding

About ATF3

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of cell population proliferation and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of CHOP-ATF3 complex. Predicted to be active in nucleus. Orthologous to human ATF3 (activating transcription factor 3). [provided by Alliance of Genome Resources, Apr 2022]

ATF3 Products(1)

mRNA Protein Name
NM_012912.2 NP_037044.1 cyclic AMP-dependent transcription factor ATF-3
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
18308734 RGD
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
18308734 RGD
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
15990869 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
18308734 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cyclic AMP-dependent transcription factor ATF-3

cAMP-dependent transcription factor ATF-3

cyclic AMP-dependent transcription factor ATF-3-like

liver regeneration factor 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (10)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-151923 ATF3 inducer 1 Inhibitor 99.50% Unkown
HY-153347 JY-2 99.75% Unkown
HY-12756A E6446 dihydrochloride 99.96% Unkown
HY-12756 E6446 ≥98.0% Unkown
HY-162384 EPIC-0628 Inhibitor 98.93% Unkown
HY-RS01129 ATF3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-155158 Anticancer agent 147 Inducer / Unkown
HY-163319 NCA029 / Unkown
HY-RS16909 Atf3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23351 Atf3 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ATF3 NCBI NCBI:467