2. Gene
  3. Scn2b - sodium voltage-gated channel beta subunit 2 Gene

Scn2b - sodium voltage-gated channel beta subunit 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as SCNB2

Gene ID: 25349 | Gene type: protein coding

About Scn2b

Summary

Enables voltage-gated Sodium Channel activity. Involved in nervous system development and response to pyrethroid. Predicted to be part of voltage-gated Sodium Channel complex. Predicted to be active in plasma membrane. Used to study visual epilepsy. Biomarker of otitis media. Human ortholog(s) of this gene implicated in familial atrial fibrillation. Orthologous to human SCN2B (sodium voltage-gated channel beta subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Scn2b Products(1)

mRNA Protein Name
NM_012877.2 NP_037009.1 sodium channel subunit beta-2 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
11238277 RGD
enables sodium channel regulator activity IDA
IDA: Inferred from direct assay
22992729 RGD
enables voltage-gated sodium channel activity IDA
IDA: Inferred from direct assay
8521473 RGD
Biological Process GO Annotation Evidence Reference Source
involved in nervous system development IEP
IEP: Inferred from expression pattern
19269275 RGD
involved in response to pyrethroid IDA
IDA: Inferred from direct assay
19026681 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in axon initial segment IDA
IDA: Inferred from direct assay
22992729 RGD
is active in node of Ranvier IDA
IDA: Inferred from direct assay
22992729 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
22992729 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium channel subunit beta-2

Sodium channel beta 2

sodium channel, voltage-gated, type II, beta polypeptide

sodium channel, voltage-gated, type II, beta subunit

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12532 SCN2B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20102 Scn2b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26605 Scn2b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Scn2b NCBI NCBI:6327