2. Gene
  3. Cd247 - Cd247 molecule Gene

Cd247 - Cd247 molecule Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Cd3z; TCRzeta

Gene ID: 25300 | Gene type: protein coding

About Cd247

Summary

Predicted to enable identical protein binding activity and protein tyrosine kinase binding activity. Involved in cell surface receptor signaling pathway. Part of T cell receptor complex. Human ortholog(s) of this gene implicated in immunodeficiency 25. Orthologous to human CD247 (CD247 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd247 Products(2)

mRNA Protein Name
NM_001205304.1 NP_001192233.1 T-cell surface glycoprotein CD3 zeta chain isoform 2 precursor
NM_170789.2 NP_740770.2 T-cell surface glycoprotein CD3 zeta chain isoform 1 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in cell surface receptor signaling pathway IDA
IDA: Inferred from direct assay
8409430 RGD
Cellular Component GO Annotation Evidence Reference Source
part of T cell receptor complex IDA
IDA: Inferred from direct assay
8409430 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

T-cell surface glycoprotein CD3 zeta chain

CD247 antigen

CD3 antigen, zeta polypeptide

T-cell receptor CD3, subunit zeta

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02214 CD247 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21508 Cd247 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28026 Cd247 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd247 NCBI NCBI:919