2. Gene
  3. Socs1 - suppressor of cytokine signaling 1 Gene

Socs1 - suppressor of cytokine signaling 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Cish1; Socs-1

Gene ID: 252971 | Gene type: protein coding

About Socs1

Summary

Predicted to enable insulin-like growth factor receptor binding activity; kinase regulator activity; and protein kinase binding activity. Involved in several processes, including response to estradiol; response to lipopolysaccharide; and response to progesterone. Acts upstream of or within cellular response to cytokine stimulus and cellular response to organic cyclic compound. Predicted to be located in cytoplasmic ribonucleoprotein granule and nucleoplasm. Predicted to be part of phosphatidylinositol 3-kinase complex. Biomarker of myocardial infarction and obesity. Human ortholog(s) of this gene implicated in ovarian carcinoma; prostate cancer; and urinary bladder Cancer. Orthologous to human SOCS1 (suppressor of cytokine signaling 1). [provided by Alliance of Genome Resources, Apr 2022]

Socs1 Products(1)

mRNA Protein Name
NM_145879.2 NP_665886.2 suppressor of cytokine signaling 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in animal organ regeneration IEP
IEP: Inferred from expression pattern
11867182 RGD
acts upstream of or within cellular response to cytokine stimulus IDA
IDA: Inferred from direct assay
19414010 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
21742974 RGD
acts upstream of or within cellular response to organic cyclic compound IDA
IDA: Inferred from direct assay
19414010 RGD
involved in cellular response to thyrotropin-releasing hormone IEP
IEP: Inferred from expression pattern
10707961 RGD
involved in cellular response to type II interferon IEP
IEP: Inferred from expression pattern
10707961 RGD
involved in cellular response to vascular endothelial growth factor stimulus IEP
IEP: Inferred from expression pattern
30771456 RGD
involved in response to cytokine IEP
IEP: Inferred from expression pattern
18424750 RGD
involved in response to erythropoietin IEP
IEP: Inferred from expression pattern
22796671 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
18325991 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
18424750 RGD
involved in response to peptide hormone IEP
IEP: Inferred from expression pattern
18325991 RGD
involved in response to progesterone IEP
IEP: Inferred from expression pattern
18325991 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
18171911 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

suppressor of cytokine signaling 1

cytokine inducible SH2-containing protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P10373 pJAK2(1001–1013) Antagonist 99.80% Unkown
HY-RS13552 SOCS1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17712 Socs1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24177 Socs1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Socs1 NCBI NCBI:8651