2. Gene
  3. Bgn - biglycan Gene

Bgn - biglycan Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as BSPG1

Gene ID: 25181 | Gene type: protein coding

About Bgn

Summary

Predicted to enable extracellular matrix binding activity and glycosaminoglycan binding activity. Involved in blood vessel remodeling. Predicted to be located in several cellular components, including cell surface; sarcolemma; and transport vesicle. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in Meester-Loeys syndrome and X-linked spondyloepimetaphyseal dysplasia. Orthologous to human BGN (biglycan). [provided by Alliance of Genome Resources, Apr 2022]

Bgn Products(1)

mRNA Protein Name
NM_017087.1 NP_058783.1 biglycan precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in blood vessel remodeling IEP
IEP: Inferred from expression pattern
11728008 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

biglycan

PG-S1

Small proteoglycan I (biglycan), bone (BSPG1) (bone/cartilage proteclycan 1 precursor)

bone/cartilage proteclycan 1

bone/cartilage proteoglycan I

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-139162 BGN3 99.47% Unkown
HY-RS01489 BGN Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24587 Bgn Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bgn NCBI NCBI:633
Mus musculus Bgn NCBI NCBI:12111