2. Gene
  3. CTH - Cth cystathionine gamma-lyase Gene

CTH - Cth cystathionine gamma-lyase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as CGL; CSE

Gene ID: 24962 | Gene type: protein coding

About CTH

Summary

Enables cystathionine beta-lyase activity. Involved in several processes, including alpha-amino acid metabolic process; glutathione metabolic process; and negative regulation of cell growth. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Used to study cataract. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and cystathioninuria. Orthologous to human CTH (cystathionine gamma-lyase). [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in glutathione metabolic process IMP
IMP: Inferred from mutant phenotype
15683713 RGD
involved in negative regulation of cell growth IMP
IMP: Inferred from mutant phenotype
15347670 RGD
involved in negative regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
15347670 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cystathionine gamma-lyase

CTL target antigen

PRB-RA

cystathionase (cystathionine gamma-lyase)

cysteine desulfhydrase

cysteine-protein sulfhydrase

gamma-cystathionase

homocysteine desulfhydrase

probasin-related antigen

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03296 CTH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15708 VSIG2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17261 Cth Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23715 Cth Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CTH NCBI NCBI:1491
Mus musculus CTH NCBI NCBI:107869