2. Gene
  3. Prss1 - serine protease 1 Gene

Prss1 - serine protease 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Try1; PTRYI; RATPTRYI

Gene ID: 24691 | Gene type: protein coding

About Prss1

Summary

Predicted to enable serine-type endopeptidase activity. Involved in response to caffeine; response to nicotine; and response to nutrient. Located in extracellular space. Biomarker of cystic fibrosis; pancreatitis; and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in pancreatitis. Orthologous to human PRSS1 (serine protease 1) and PRSS3 (serine protease 3). [provided by Alliance of Genome Resources, Apr 2022]

Prss1 Products(1)

mRNA Protein Name
NM_012635.1 NP_036767.1 serine protease 1 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in response to acetaldehyde IEP
IEP: Inferred from expression pattern
2422952 RGD
involved in response to caffeine IDA
IDA: Inferred from direct assay
2726780 RGD
involved in response to nicotine IDA
IDA: Inferred from direct assay
2460970 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
2363685 RGD
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
3833185 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine protease 1

anionic trypsin I

anionic trypsin-1

beta-trypsin

cationic trypsinogen

pancreatic trypsin 1

pretrypsinogen I

protease, serine 1

protease, serine, 1 (trypsin 1)

protease, serine, 2

trypsin I

trypsin-1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11245 PRSS1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18295 Prss1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24773 Prss1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prss1 NCBI NCBI:5644
Mus musculus Prss1 NCBI NCBI:114228