2. Gene
  3. Ephb1 - Eph receptor B1 Gene

Ephb1 - Eph receptor B1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Erk; elk; Ephb2

Gene ID: 24338 | Gene type: protein coding

About Ephb1

Summary

Enables protein tyrosine kinase activity. Involved in hindbrain tangential cell migration and protein autophosphorylation. Acts upstream of or within dendritic spine development and immunological synapse formation. Predicted to be located in several cellular components, including early endosome membrane; filopodium tip; and membrane raft. Predicted to be part of receptor complex. Predicted to be active in glutamatergic synapse and neuron projection. Predicted to be integral component of plasma membrane. Orthologous to human EphB1 (EPH receptor B1). [provided by Alliance of Genome Resources, Apr 2022]

Ephb1 Products(1)

mRNA Protein Name
NM_001104528.1 NP_001097998.1 ephrin type-B receptor 1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein tyrosine kinase activity IDA
IDA: Inferred from direct assay
2017163 RGD
enables protein tyrosine kinase activity IMP
IMP: Inferred from mutant phenotype
2485255 RGD
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within dendritic spine development IGI
IGI: Inferred from genetic interaction
17310244 RGD
involved in hindbrain tangential cell migration IMP
IMP: Inferred from mutant phenotype
28276447 RGD
acts upstream of or within immunological synapse formation IGI
IGI: Inferred from genetic interaction
17310244 RGD
involved in protein autophosphorylation IDA
IDA: Inferred from direct assay
2017163 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ephrin type-B receptor 1

ELK-related protein tyrosine kinase

Eph receptor B2 (ELK-related protein tyrosine kinase)

tyrosine-protein kinase receptor EPH-2

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-115481 EphB1-IN-1 Inhibitor 99.87% Unkown
HY-170517 PKMYT1-IN-8 Inhibitor 99.31% Unkown
HY-RS04433 EPHB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18062 Ephb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24537 Ephb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ephb1 NCBI NCBI:2047
Mus musculus Ephb1 NCBI NCBI:270190
Macaca mulatta Ephb1 NCBI NCBI:717211