2. Gene
  3. Hpdl - 4-hydroxyphenylpyruvate dioxygenase-like Gene

Hpdl - 4-hydroxyphenylpyruvate dioxygenase-like Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gloxd1; A830048M07Rik

Gene ID: 242642 | Gene type: protein coding

About Hpdl

Summary

Predicted to enable 4-hydroxyphenylpyruvate dioxygenase activity and metal ion binding activity. Predicted to be involved in aromatic amino acid family metabolic process. Located in mitochondrion. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia. Orthologous to human HPDL (4-hydroxyphenylpyruvate dioxygenase like). [provided by Alliance of Genome Resources, Apr 2022]

Hpdl Products(1)

mRNA Protein Name
NM_146256.3 NP_666368.1 4-hydroxyphenylpyruvate dioxygenase-like protein
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrion IDA
IDA: Inferred from direct assay
32707086 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

4-hydroxyphenylpyruvate dioxygenase-like protein

glyoxalase domain containing 1

glyoxalase domain-containing protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (10)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-131183 PROTAC PD-1/PD-L1 degrader-1 Inhibitor 99.52% Unkown
HY-P2477 Human PD-L1 inhibitor IV Inhibitor 99.68% Unkown
HY-P2478A Human PD-L1 inhibitor V TFA Inhibitor / Unkown
HY-P2474 Human PD-L1 inhibitor I 98.93% Unkown
HY-P2478 Human PD-L1 inhibitor V Inhibitor 99.04% Unkown
HY-130625 PD-1/PD-L1-IN 6 Inhibitor / Unkown
HY-155740 PD-1/PD-L1-IN-32 Inhibitor / Unkown
HY-168080 PD-1/PD-L1-IN-51 Inhibitor / Unkown
HY-RS06336 HPDL Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22202 Hpdl Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hpdl NCBI NCBI:84842