2. Gene
  3. Adcyap1r1 - ADCYAP receptor type I Gene

Adcyap1r1 - ADCYAP receptor type I Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as PAC1-R; PACAPR1; PACAP-R1; PACAPR1A; PACAP-R1A

Gene ID: 24167 | Gene type: protein coding

About Adcyap1r1

Summary

Enables Adenylate Cyclase binding activity; neuropeptide binding activity; and small GTPase binding activity. Involved in several processes, including activation of Phospholipase C activity; cAMP-mediated signaling; and positive regulation of intracellular signal transduction. Located in several cellular components, including bicellular tight junction; caveola; and rough endoplasmic reticulum. Biomarker of cystitis. Orthologous to human ADCYAP1R1 (ADCYAP receptor type I). [provided by Alliance of Genome Resources, Apr 2022]

Adcyap1r1 Products(6)

mRNA Protein Name
NM_001270579.1 NP_001257508.1 pituitary adenylate cyclase-activating polypeptide type I receptor isoform a precursor
NM_001270580.1 NP_001257509.1 pituitary adenylate cyclase-activating polypeptide type I receptor isoform c precursor
NM_001270581.1 NP_001257510.1 pituitary adenylate cyclase-activating polypeptide type I receptor isoform d precursor
NM_001270582.1 NP_001257511.1 pituitary adenylate cyclase-activating polypeptide type I receptor isoform d precursor
NM_001270583.1 NP_001257512.1 pituitary adenylate cyclase-activating polypeptide type I receptor isoform e precursor
NM_133511.2 NP_598195.1 pituitary adenylate cyclase-activating polypeptide type I receptor isoform b precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables adenylate cyclase binding IDA
IDA: Inferred from direct assay
17680996 RGD
enables neuropeptide binding IDA
IDA: Inferred from direct assay
16905223 RGD
enables small GTPase binding IDA
IDA: Inferred from direct assay
11353814 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cAMP/PKA signal transduction IDA
IDA: Inferred from direct assay
8396727 RGD
involved in development of primary female sexual characteristics IEP
IEP: Inferred from expression pattern
17065411 RGD
involved in multicellular organismal response to stress IEP
IEP: Inferred from expression pattern
19181454 RGD
involved in negative regulation of response to reactive oxygen species IDA
IDA: Inferred from direct assay
16905223 RGD
involved in positive regulation of cAMP/PKA signal transduction IDA
IDA: Inferred from direct assay
16905223 RGD
involved in positive regulation of calcium ion transport into cytosol IMP
IMP: Inferred from mutant phenotype
16401644 RGD
involved in positive regulation of inositol phosphate biosynthetic process IDA
IDA: Inferred from direct assay
8396727 RGD
involved in positive regulation of small GTPase mediated signal transduction IMP
IMP: Inferred from mutant phenotype
18541665 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
15976009 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
16820708 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
18592413 RGD
Cellular Component GO Annotation Evidence Reference Source
located in bicellular tight junction IDA
IDA: Inferred from direct assay
16626868 RGD
located in caveola IDA
IDA: Inferred from direct assay
17680996 RGD
located in cell surface IDA
IDA: Inferred from direct assay
15968088 RGD
located in endosome IDA
IDA: Inferred from direct assay
19416476 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pituitary adenylate cyclase-activating polypeptide type I receptor

ADCYAP receptor type 1

PACAP type I receptor

PACAP type IA receptor

PACAP-R-1

PACAP-R-1A

adenylate cyclase activating polypeptide 1 (pituitary) receptor type I

adenylate cyclase activating polypeptide 1 receptor 1

adenylate cyclase activating polyp

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00337 ADCYAP1R1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18214 Adcyap1r1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24691 Adcyap1r1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adcyap1r1 NCBI NCBI:117