1. Gene
  2. Abce1 - ATP-binding cassette, sub-family E (OABP), member 1 Gene

Abce1 - ATP-binding cassette, sub-family E (OABP), member 1 Gene

Mus musculus

Also known as RLI; Oabp; RNS41; RNS4I; Rnaseli

Gene ID: 24015 | Gene type: protein coding

About Abce1

Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. [provided by RefSeq, Jul 2008]

Abce1 Products(2)

mRNA Protein Name
NM_015751.2 NP_056566.2 ATP-binding cassette sub-family E member 1
NM_015751.2 NP_056566.2 ATP-binding cassette sub-family E member 1
Protein Preferred Names Protein Names

ATP-binding cassette sub-family E member 1

ATP-binding cassette, subfamily E, member 1

RNS4l (Eye)

RNase L inhibitor

ribonuclease 4 inhibitor

ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) inhibitor

Orthologs Information

Species Symbol Source ID
Homo sapiens Abce1 NCBI NCBI:6059