Psmc4 - proteasome (prosome, macropain) 26S subunit, ATPase, 4 Gene

Mus musculus

Also known as CIP21; MIP224

Gene ID: 23996 | Gene type: protein coding

About Psmc4

Summary

Predicted to enable proteasome-activating activity. Acts upstream of or within blastocyst development. Part of Proteasome accessory complex. Is expressed in several structures, including alimentary system; cranial ganglion; early conceptus; gonad; and liver lobe. Used to study amyotrophic lateral sclerosis. Orthologous to human PSMC4 (Proteasome 26S subunit, ATPase 4). [provided by Alliance of Genome Resources, Apr 2022]

Psmc4 Products(1)

mRNA	Protein	Name
NM_011874.2	NP_036004.2	26S proteasome regulatory subunit 6B

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within blastocyst development	IMP IMP: Inferred from mutant phenotype	10945464	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
part of proteasome accessory complex	IDA IDA: Inferred from direct assay	16857966	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

26S proteasome regulatory subunit 6B

26S protease regulatory subunit 6B	26S proteasome AAA-ATPase subunit RPT3
CAR interacing protein 21	CAR interacting protein 21
MB67-interacting protein	TAT-binding protein 7
TBP-7	proteasome 26S ATPase subunit 4
proteasome 26S subunit ATPase 4

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11314	PSMC4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21702	Psmc4 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Psmc4	NCBI	NCBI:5704

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