Zdhhc5 - zinc finger, DHHC domain containing 5 Gene

Mus musculus

Also known as Zisp; 1110032A17Rik

Gene ID: 228136 | Gene type: protein coding

About Zdhhc5

Summary

Enables palmitoyltransferase activity. Involved in positive regulation of pattern recognition receptor signaling pathway; positive regulation of protein localization to phagocytic vesicle; and positive regulation of protein localization to plasma membrane. Acts upstream of or within protein palmitoylation. Located in dendrite; phagocytic vesicle; and plasma membrane. Is expressed in early conceptus; eye; heart; oocyte; and trunk somite. Orthologous to human ZDHHC5 (zinc finger DHHC-type palmitoyltransferase 5). [provided by Alliance of Genome Resources, Apr 2022]

Zdhhc5 Products(1)

mRNA	Protein	Name
NM_144887.4	NP_659136.1	palmitoyltransferase ZDHHC5

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables palmitoyltransferase activity	IDA IDA: Inferred from direct assay	22325201	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	21820437	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of pattern recognition receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	31649195	MGI
involved in positive regulation of protein localization to phagocytic vesicle	IMP IMP: Inferred from mutant phenotype	31649195	MGI
involved in positive regulation of protein localization to plasma membrane	IMP IMP: Inferred from mutant phenotype	31649195	MGI
involved in positive regulation of pyroptotic inflammatory response	IMP IMP: Inferred from mutant phenotype	38530158	MGI
acts upstream of or within protein palmitoylation	IDA IDA: Inferred from direct assay	22325201	MGI
acts upstream of or within protein palmitoylation	IMP IMP: Inferred from mutant phenotype	21820437	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in dendrite	IDA IDA: Inferred from direct assay	22325201	MGI
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	22325201	MGI
is active in glutamatergic synapse	IEP IEP: Inferred from expression pattern	22325201	MGI
located in phagocytic vesicle	IDA IDA: Inferred from direct assay	31649195	MGI
located in plasma membrane	IDA IDA: Inferred from direct assay	21820437	MGI
is active in postsynapse	IDA IDA: Inferred from direct assay	22325201	MGI
is active in postsynapse	IEP IEP: Inferred from expression pattern	22325201	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

palmitoyltransferase ZDHHC5

DHHC-5	probable palmitoyltransferase ZDHHC5
zinc finger DHHC domain-containing protein 5

Zdhhc5 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Zdhhc5	Q8VDZ4	GOLGA7B	Mus musculus	Q9D428	Anti Bait CoIP	31402609

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16022	ZDHHC5 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS21221	Zdhhc5 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS27737	Zdhhc5 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Zdhhc5	NCBI	NCBI:25921

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