2. Gene
  3. Mark1 - MAP/microtubule affinity regulating kinase 1 Gene

Mark1 - MAP/microtubule affinity regulating kinase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Emk3; Par-1c; mPar-1c; mKIAA1477; B930025N23Rik

Gene ID: 226778 | Gene type: protein coding

About Mark1

Summary

Predicted to enable several functions, including ATP binding activity; phospholipid binding activity; and protein kinase activity. Involved in establishment of mitochondrion localization and regulation of dendrite development. Predicted to be located in cytoskeleton; dendrite; and plasma membrane. Predicted to be active in cytoplasm. Is expressed in dorsal root ganglion; facial ganglion; glossopharyngeal ganglion; and trigeminal ganglion. Orthologous to human MARK1 (microtubule affinity regulating kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Mark1 Products(2)

mRNA Protein Name
NM_001378876.1 NP_001365805.1 serine/threonine-protein kinase MARK1 isoform 1
NM_145515.2 NP_663490.2 serine/threonine-protein kinase MARK1 isoform 2
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in establishment of mitochondrion localization IMP
IMP: Inferred from mutant phenotype
18492799 MGI
involved in regulation of dendrite development IMP
IMP: Inferred from mutant phenotype
18492799 MGI
involved in regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
18492799 MGI
involved in regulation of postsynapse assembly IDA
IDA: Inferred from direct assay
27829159 MGI
involved in regulation of postsynapse assembly IEP
IEP: Inferred from expression pattern
27829159 MGI
involved in regulation of postsynapse assembly IMP
IMP: Inferred from mutant phenotype
27829159 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
27829159 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
27829159 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
27829159 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
27829159 MGI
is active in postsynapse IEP
IEP: Inferred from expression pattern
27829159 MGI
is active in postsynapse IMP
IMP: Inferred from mutant phenotype
27829159 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein kinase MARK1

ELKL motif serine-threonine protein kinase 3

PAR1 homolog c

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-120877 MRT199665 99.74% Unkown
HY-139604 PCC0208017 99.56% Unkown
HY-120877A (R)-MRT199665 98.70% Unkown
HY-RS08149 MARK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21640 Mark1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28158 Mark1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mark1 NCBI NCBI:4139