2. Gene
  3. Mapk4 - mitogen-activated protein kinase 4 Gene

Mapk4 - mitogen-activated protein kinase 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Erk3; Prkm4; p63Mapk; A330097D03Rik

Gene ID: 225724 | Gene type: protein coding

About Mapk4

Summary

Enables protein heterodimerization activity; protein homodimerization activity; and protein kinase binding activity. Predicted to be involved in intracellular signal transduction. Predicted to act upstream of or within phosphorylation. Located in cytoplasm and nucleus. Is expressed in female associated reproductive structure; ureteric tip; and ureteric trunk. Orthologous to human MAPK4 (mitogen-activated protein kinase 4). [provided by Alliance of Genome Resources, Apr 2022]

Mapk4 Products(2)

mRNA Protein Name
NM_001360936.1 NP_001347865.1 mitogen-activated protein kinase 4 isoform 2
NM_172632.2 NP_766220.2 mitogen-activated protein kinase 4 isoform 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein heterodimerization activity IPI
IPI: Inferred from physical interaction
16973613 MGI
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
16973613 MGI
enables protein kinase binding IPI
IPI: Inferred from physical interaction
16973613 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
16973613 MGI
located in nucleus IDA
IDA: Inferred from direct assay
16973613 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitogen-activated protein kinase 4

ERK-4

Erk3-related

MAP kinase 4

MAPK 4

extracellular signal-regulated kinase 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-154987 MARK4 inhibitor 3 98.23% Unkown
HY-172781 HDAC6-IN-55 Inhibitor / Unkown
HY-RS08116 MAPK4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17984 Mapk4 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24455 Mapk4 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mapk4 NCBI NCBI:5596