Slc32a1 - solute carrier family 32 (GABA vesicular transporter), member 1 Gene

Mus musculus

Also known as VGAT; Viaat

Gene ID: 22348 | Gene type: protein coding

About Slc32a1

Summary

Enables gamma-aminobutyric acid:proton symporter activity and glycine transmembrane transporter activity. Acts upstream of or within glycine transport. Located in several cellular components, including cone cell pedicle; dendrite terminus; and inhibitory synapse. Is expressed in several structures, including cardiovascular system; eye; genitourinary system; nervous system; and skeleton. Used to study temporal lobe epilepsy. Orthologous to human SLC32A1 (solute carrier family 32 member 1). [provided by Alliance of Genome Resources, Apr 2022]

Slc32a1 Products(1)

mRNA	Protein	Name
NM_009508.2	NP_033534.2	vesicular inhibitory amino acid transporter

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables gamma-aminobutyric acid:proton antiporter activity	IDA IDA: Inferred from direct assay	9395291	MGI
enables glycine transmembrane transporter activity	IDA IDA: Inferred from direct assay	9395291	MGI
enables glycine:proton antiporter activity	IDA IDA: Inferred from direct assay	16701208	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in gamma-aminobutyric acid import	IDA IDA: Inferred from direct assay	9395291	MGI
acts upstream of or within glycine transport	IDA IDA: Inferred from direct assay	9395291	MGI
involved in glycine transport	IDA IDA: Inferred from direct assay	16701208	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cell surface	IDA IDA: Inferred from direct assay	29107521	MGI
located in cell tip	IDA IDA: Inferred from direct assay	12115694	MGI
located in cone cell pedicle	IDA IDA: Inferred from direct assay	12115694	MGI
located in dendrite terminus	IDA IDA: Inferred from direct assay	12115694	MGI
located in inhibitory synapse	IDA IDA: Inferred from direct assay	16814779	MGI
located in neuron projection	IDA IDA: Inferred from direct assay	12115694	MGI
located in neuron projection terminus	IDA IDA: Inferred from direct assay	12115694	MGI
located in presynaptic active zone	IDA IDA: Inferred from direct assay	23258346	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

vesicular inhibitory amino acid transporter

GABA and glycine transporter	mVGAT
mVIAAT	solute carrier family 32 member 1
vasicular inhibitory amino acid transporter 10D	vesicular GABA and glycine transporter
vesicular GABA transporter a form

Slc32a1 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P87075	SLC32A1/VGAT Antibody (YA6768)	IHC-F, IHC-P	Mouse, Rat

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13190	SLC32A1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc32a1	NCBI	NCBI:140679

Name
Email *

	Sorry, but the email address you supplied was invalid.