2. Gene
  3. Vegfb - vascular endothelial growth factor B Gene

Vegfb - vascular endothelial growth factor B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Vrf; VEGF-B

Gene ID: 22340 | Gene type: protein coding

About Vegfb

Summary

Enables identical protein binding activity. Acts upstream of or within cardiac muscle contraction; coronary vasculature development; and protein O-linked glycosylation. Located in extracellular region. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and musculoskeletal system. Human ortholog(s) of this gene implicated in myocardial infarction and pulmonary hypertension. Orthologous to human VEGFB (vascular endothelial growth factor B). [provided by Alliance of Genome Resources, Apr 2022]

Vegfb Products(2)

mRNA Protein Name
NM_001185164.1 NP_001172093.1 vascular endothelial growth factor B isoform Vegf-b167 precursor
NM_011697.3 NP_035827.1 vascular endothelial growth factor B isoform Vegf-b186 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
8702615 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
8702615 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cardiac muscle contraction IMP
IMP: Inferred from mutant phenotype
10666423 MGI
acts upstream of or within coronary vasculature development IMP
IMP: Inferred from mutant phenotype
10666423 MGI
acts upstream of or within heart development IMP
IMP: Inferred from mutant phenotype
10666423 MGI
acts upstream of or within protein O-linked glycosylation IDA
IDA: Inferred from direct assay
8702615 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular region IDA
IDA: Inferred from direct assay
8702615 MGI
located in intracellular anatomical structure IDA
IDA: Inferred from direct assay
8702615 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vascular endothelial growth factor B

VEGF-related factor

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P990540 Anti-VEGFB Antibody (CSL346) / Phase 2
Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P10831 GNQWFI Antagonist 99.45% Unkown
HY-P10550 VGB4 Antagonist / Unkown
HY-RS15636 VEGFB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18083 Vegfb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24557 Vegfb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990758 Reflocibart / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vegfb NCBI NCBI:7423