Urod - uroporphyrinogen decarboxylase Gene

Mus musculus

Also known as UPD; Uro-d

Gene ID: 22275 | Gene type: protein coding

About Urod

Summary

This gene encodes an enzyme that catalyzes the conversion of uroporphyrinogen-III to coproporphyrinogen-III, an intermediate step in heme biosynthesis. Homozygous knockout mice for this gene exhibit embryonic lethality. [provided by RefSeq, Aug 2015]

Urod Products(1)

mRNA	Protein	Name
NM_009478.4	NP_033504.2	uroporphyrinogen decarboxylase

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables uroporphyrinogen decarboxylase activity	IDA IDA: Inferred from direct assay	8661721	MGI
enables uroporphyrinogen decarboxylase activity	IMP IMP: Inferred from mutant phenotype	11134514	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in heme A biosynthetic process	IMP IMP: Inferred from mutant phenotype	17360334	MGI
involved in heme B biosynthetic process	IMP IMP: Inferred from mutant phenotype	17360334	MGI
involved in heme O biosynthetic process	IMP IMP: Inferred from mutant phenotype	17360334	MGI
acts upstream of or within heme biosynthetic process	IMP IMP: Inferred from mutant phenotype	17360334	MGI
acts upstream of or within heme metabolic process	IMP IMP: Inferred from mutant phenotype	11134514	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in cytosol	IDA IDA: Inferred from direct assay	12297827	MGI
located in cytosol	IDA IDA: Inferred from direct assay	17360334	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

uroporphyrinogen decarboxylase

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-176305S	Neurofilament, U-15N		/	Unkown
HY-RS15509	UROD Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS21453	Urod Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS27971	Urod Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Urod	NCBI	NCBI:7389

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