2. Gene
  3. Ucn - urocortin Gene

Ucn - urocortin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ucn1; Mpv17

Gene ID: 22226 | Gene type: protein coding

About Ucn

Summary

This gene encodes a member of the corticotropin-releasing hormone peptide family that participates in coordinating autonomic, endocrine, and behavioral responses to stress. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional hormone. Mice lacking the encoded protein exhibit a heightened anxiety-like behaviors and a significantly reduced acoustic startle response. [provided by RefSeq, Sep 2016]

Ucn Products(2)

mRNA Protein Name
NM_001346010.1 NP_001332939.1 urocortin preproprotein
NM_021290.2 NP_067265.1 urocortin preproprotein
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
12091910 MGI
NOT involved in prepulse inhibition IMP
IMP: Inferred from mutant phenotype
12192058 MGI
involved in response to auditory stimulus IMP
IMP: Inferred from mutant phenotype
12091910 MGI
NOT involved in response to immobilization stress IMP
IMP: Inferred from mutant phenotype
12091910 MGI
NOT involved in response to starvation IMP
IMP: Inferred from mutant phenotype
12091910 MGI
involved in startle response IMP
IMP: Inferred from mutant phenotype
12192058 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

urocortin

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-13661 7-Hydroxystaurosporine / Phase 2
Pre-clinical Phase
Bioactive Molecules (11)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P1858A Urocortin III, mouse TFA Activator 95.93% Unkown
HY-105416 Calphostin C Inhibitor 99.00% Unkown
HY-108262 UCN-02 Inhibitor ≥98.0% Unkown
HY-P1858 Urocortin III, mouse Activator / Unkown
HY-RS15407 UCN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15408 UCN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15409 UCN3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17732 Ucn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21451 Ucn3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24197 Ucn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27969 Ucn3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ucn NCBI NCBI:7349