2. Gene
  3. Usp10 - ubiquitin specific peptidase 10 Gene

Usp10 - ubiquitin specific peptidase 10 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as UBPO; Uchrp; mKIAA0190; 2610014N07Rik

Gene ID: 22224 | Gene type: protein coding

About Usp10

Summary

Predicted to enable cysteine-type peptidase activity; p53 binding activity; and transmembrane transporter binding activity. Predicted to be involved in several processes, including DNA damage response, signal transduction by p53 class mediator; cellular response to interleukin-1; and negative regulation of I-kappaB kinase/NF-kappaB signaling. Predicted to act upstream of or within DNA repair and Autophagy. Predicted to be located in cytoplasm; intermediate filament cytoskeleton; and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in cytosol; early endosome; and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human USP10 (ubiquitin specific peptidase 10). [provided by Alliance of Genome Resources, Apr 2022]

Usp10 Products(2)

mRNA Protein Name
NM_001310630.1 NP_001297559.1 ubiquitin carboxyl-terminal hydrolase 10 isoform 2
NM_009462.2 NP_033488.1 ubiquitin carboxyl-terminal hydrolase 10 isoform 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
35987808 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase 10

deubiquitinating enzyme 10

ubiquintin c-terminal hydrolase related polypeptide

ubiquitin specific protease 10

ubiquitin thioesterase 10

ubiquitin thiolesterase 10

ubiquitin-specific-processing protease 10

Usp10 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Usp10 P52479 Mapt Mus musculus P10637
Anti Bait CoIP
35987808
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-175538 USP10-IN-4 / Phase 3
Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12990 Spautin-1 99.54% Unkown
HY-153886 Wu-5 99.34% Unkown
HY-163622 USP10-IN-3 98.00% Unkown
HY-125015 USP10-IN-1 Inhibitor / Unkown
HY-RS15521 USP10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15543 USP32 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17175 Usp10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23625 Usp10 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Usp10 NCBI NCBI:9100