Ttf1 - transcription termination factor, RNA polymerase I Gene

Mus musculus

Also known as TTF-1; TTF-I

Gene ID: 22130 | Gene type: protein coding

About Ttf1

Summary

Enables DNA binding activity and chromatin binding activity. Acts upstream of or within chromatin remodeling; termination of RNA polymerase I transcription; and transcription initiation from RNA polymerase I promoter. Located in nucleus. Is expressed in early conceptus and genitourinary system. Orthologous to human TTF1 (transcription termination factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Ttf1 Products(1)

mRNA	Protein	Name
NM_009442.2	NP_033468.2	transcription termination factor 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA binding	IDA IDA: Inferred from direct assay	7720715	MGI
enables chromatin binding	IDA IDA: Inferred from direct assay	9049305	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	10589839	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within chromatin remodeling	IDA IDA: Inferred from direct assay	9049305	MGI
acts upstream of or within termination of RNA polymerase I transcription	IDA IDA: Inferred from direct assay	7720715	MGI
involved in termination of RNA polymerase I transcription	IDA IDA: Inferred from direct assay	10589839	MGI
involved in transcription by RNA polymerase I	IDA IDA: Inferred from direct assay	20513429	MGI
acts upstream of or within transcription initiation at RNA polymerase I promoter	IDA IDA: Inferred from direct assay	7720715	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleolus	IDA IDA: Inferred from direct assay	20513429	MGI
located in nucleoplasm	IDA IDA: Inferred from direct assay	20513429	MGI
located in nucleus	IDA IDA: Inferred from direct assay	7720715	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

transcription termination factor 1

RNA polymerase I termination factor

transcription termination factor I

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09327	NKX2-1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS15222	TTF1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS21450	Ttf1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS27968	Ttf1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ttf1	NCBI	NCBI:7270

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