Trpc5 - transient receptor potential cation channel, subfamily C, member 5 Gene

Mus musculus

Also known as CCE2; TRP5; TRP-5; Trrp5

Gene ID: 22067 | Gene type: protein coding

About Trpc5

Summary

Enables inositol 1,4,5 trisphosphate binding activity. Involved in neuron apoptotic process and phosphatidylserine exposure on apoptotic cell surface. Predicted to be located in several cellular components, including growth cone; membrane raft; and neuronal cell body. Predicted to be part of Calcium Channel complex. Predicted to be integral component of plasma membrane. Is expressed in brain; cochlea; dorsal root ganglion; and vagus ganglion. Orthologous to human TRPC5 (transient receptor potential cation channel subfamily C member 5). [provided by Alliance of Genome Resources, Apr 2022]

Trpc5 Products(1)

mRNA	Protein	Name
NM_009428.3	NP_033454.1	short transient receptor potential channel 5

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables inositol 1,4,5 trisphosphate binding	IDA IDA: Inferred from direct assay	14505576	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	14505576	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in neuron apoptotic process	IMP IMP: Inferred from mutant phenotype	32110987	MGI
involved in phosphatidylserine exposure on apoptotic cell surface	IMP IMP: Inferred from mutant phenotype	32110987	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in presynapse	IDA IDA: Inferred from direct assay	17928293	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

short transient receptor potential channel 5

capacitative calcium entry channel 2	transient receptor protein 5
trp-related protein 5	vtransient receptor potential cation channel, subfamily C, member 5

Related Agents

Approval

Bioactive Molecules (8)

Cat. No.	Product Name	Purity	Rare Diseases
HY-17386	Rosiglitazone	99.94%	Yes
HY-14600	Rosiglitazone maleate	99.73%	Yes
HY-17386A	Rosiglitazone hydrochloride	99.81%	Yes
HY-30234A	Clemizole hydrochloride	99.99%	Yes
HY-17386B	Rosiglitazone potassium	/	Unkown
HY-14600R	Rosiglitazone maleate (Standard)	/	Unkown
HY-30234	Clemizole	/	Unkown
HY-B0700	Rosiglitazone sodium	/	Unkown

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-162584	TRPC4/5-IN-2	Inhibitor	/	Phase 2

Pre-clinical Phase

Bioactive Molecules (25)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-101507	Zerencotrep	Inhibitor	99.47%	Unkown
HY-133168	Englerin A	Activator	99.50%	Unkown
HY-12949	ML204	Inhibitor	98.45%	Unkown
HY-112302	HC-070	Antagonist	99.74%	Unkown
HY-122051	AC1903	Inhibitor	99.80%	Unkown
HY-128205	BTD	Inhibitor	99.78%	Unkown
HY-12949A	ML204 hydrochloride	Inhibitor	99.74%	Unkown
HY-132813	Evifacotrep	Antagonist	99.65%	Unkown
HY-133012	GFB-8438	Inhibitor	99.74%	Unkown
HY-145150	TRPC5-IN-1	Inhibitor	98.97%	Unkown
HY-17386S	Rosiglitazone-d3		/	Unkown
HY-128561	AM12	Activator	/	Unkown
HY-142030	TRPC5 modulator-1	Modulator	/	Unkown
HY-144205	TRPC5-IN-2	Inhibitor	/	Unkown
HY-144208	TRPC5-IN-3	Inhibitor	/	Unkown
HY-144429	TRPC5-IN-4	Inhibitor	/	Unkown
HY-146155	TRPC4/5-IN-1	Inhibitor	/	Unkown
HY-162090	TRPC antagonist 1	Antagonist	/	Unkown
HY-172106	TRPC5-IN-5	Inhibitor	/	Unkown
HY-172600	TRPC6 antagonist-1	Antagonist	/	Unkown
HY-RS15108	TRPC5 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-W707161	4-Methyl-2-(1-piperidinyl)-quinoline-d10		/	Unkown
HY-17386S1	Rosiglitazone-d4		/	Unkown
HY-RS16614	Trpc5 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS23049	Trpc5 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Trpc5	NCBI	NCBI:7224

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