2. Gene
  3. Tns1 - tensin 1 Gene

Tns1 - tensin 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Tns; 1110018I21Rik; 1200014E20Rik; E030018G17Rik; E030037J05Rik

Gene ID: 21961 | Gene type: protein coding

About Tns1

Summary

Predicted to enable actin binding activity. Acts upstream of or within cell-substrate junction assembly and fibroblast migration. Located in focal adhesion. Is expressed in several structures, including future midbrain; gut; metanephros; nasal process; and yolk sac. Orthologous to human TNS1 (tensin 1). [provided by Alliance of Genome Resources, Apr 2022]

Tns1 Products(7)

mRNA Protein Name
NM_001289895.2 NP_001276824.1 tensin-1 isoform b
NM_001413787.1 NP_001400716.1 tensin-1 isoform c
NM_001413788.1 NP_001400717.1 tensin-1 isoform d
NM_001413789.1 NP_001400718.1 tensin-1 isoform d
NM_001413790.1 NP_001400719.1 tensin-1 isoform e
NM_001413791.1 NP_001400720.1 tensin-1 isoform f
NM_027884.4 NP_082160.3 tensin-1 isoform a
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cell-substrate junction assembly IMP
IMP: Inferred from mutant phenotype
9087448 MGI
acts upstream of or within fibroblast migration IMP
IMP: Inferred from mutant phenotype
11792844 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cell-substrate junction IDA
IDA: Inferred from direct assay
9087448 MGI
located in focal adhesion IDA
IDA: Inferred from direct assay
9087448 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tensin-1

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14867 TNS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19524 Pycard Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21447 Tns1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27965 Tns1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tns1 NCBI NCBI:7145