2. Gene
  3. Tnnc1 - troponin C, cardiac/slow skeletal Gene

Tnnc1 - troponin C, cardiac/slow skeletal Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as TnC; cTnC; cTnI; tncc

Gene ID: 21924 | Gene type: protein coding

About Tnnc1

Summary

Enables actin filament binding activity. Involved in regulation of ATPase activity and regulation of muscle filament sliding speed. Acts upstream of or within transition between fast and slow fiber. Predicted to be located in contractile fiber. Predicted to be part of cardiac Troponin complex. Is expressed in several structures, including alimentary system; heart; liver; metanephros; and skeletal muscle. Used to study hypertrophic cardiomyopathy 13. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1Z; hypertrophic cardiomyopathy; and hypertrophic cardiomyopathy 13. Orthologous to human TNNC1 (troponin C1, slow skeletal and cardiac type). [provided by Alliance of Genome Resources, Apr 2022]

Tnnc1 Products(1)

mRNA Protein Name
NM_009393.4 NP_033419.1 troponin C, slow skeletal and cardiac muscles
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables actin filament binding IDA
IDA: Inferred from direct assay
8785301 MGI
Biological Process GO Annotation Evidence Reference Source
involved in regulation of ATP-dependent activity IDA
IDA: Inferred from direct assay
8785301 MGI
involved in regulation of muscle filament sliding speed IMP
IMP: Inferred from mutant phenotype
10747195 MGI
acts upstream of or within transition between fast and slow fiber IDA
IDA: Inferred from direct assay
18978355 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

troponin C, slow skeletal and cardiac muscles

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14848 TNNC1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19041 Tnnc1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25531 Tnnc1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnnc1 NCBI NCBI:7134