Tle2 - transducin-like enhancer of split 2 Gene

Mus musculus

Also known as Grg2; mKIAA4188

Gene ID: 21886 | Gene type: protein coding

About Tle2

Summary

Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of canonical Wnt signaling pathway and negative regulation of transcription, DNA-templated. Predicted to act upstream of or within Wnt signaling pathway. Predicted to be located in focal adhesion and nuclear body. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; integumental system; limb; and sensory organ. Orthologous to human TLE2 (TLE family member 2, transcriptional corepressor). [provided by Alliance of Genome Resources, Apr 2022]

Tle2 Products(2)

mRNA	Protein	Name
NM_001252401.1	NP_001239330.1	transducin-like enhancer protein 2 isoform 2
NM_019725.2	NP_062699.1	transducin-like enhancer protein 2 isoform 1

Protein Preferred Names

Protein Names

transducin-like enhancer protein 2

groucho-related protein

transducin-like enhancer of split 2, homolog of Drosophila E(spl)

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14564	TLE2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS20827	Tle2 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS27341	Tle2 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tle2	NCBI	NCBI:7089

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