2. Gene
  3. Gmds - GDP-mannose 4, 6-dehydratase Gene

Gmds - GDP-mannose 4, 6-dehydratase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 218138 | Gene type: protein coding

About Gmds

Summary

Predicted to enable GDP-mannose 4,6-dehydratase activity. Predicted to be involved in 'de novo' GDP-L-fucose biosynthetic process and GDP-mannose metabolic process. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; ear; nervous system; respiratory system; and skeleton. Human ortholog(s) of this gene implicated in open-angle glaucoma. Orthologous to human GMDS (GDP-mannose 4,6-dehydratase). [provided by Alliance of Genome Resources, Apr 2022]

Gmds Products(1)

mRNA Protein Name
NM_146041.2 NP_666153.1 GDP-mannose 4,6 dehydratase
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables GDP-mannose 4,6-dehydratase activity IDA
IDA: Inferred from direct assay
29033318 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in cytosol IDA
IDA: Inferred from direct assay
29033318 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

GDP-mannose 4,6 dehydratase

GDP-D-mannose dehydratase

GMD

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05515 GMDS Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21350 Gmds Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gmds NCBI NCBI:2762