2. Gene
  3. Sycp3 - synaptonemal complex protein 3 Gene

Sycp3 - synaptonemal complex protein 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cor1; Scp3

Gene ID: 20962 | Gene type: protein coding

About Sycp3

Summary

Predicted to enable DNA binding activity. Involved in meiotic chromosome segregation and spermatogenesis. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; meiosis I cell cycle process; and sperm chromatin condensation. Located in condensed chromosome and male germ cell nucleus. Is expressed in several structures, including adrenal gland; alimentary system; brain; genitourinary system; and primordial germ cell. Used to study azoospermia. Human ortholog(s) of this gene implicated in spermatogenic failure 4. Orthologous to human SYCP3 (synaptonemal complex protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Sycp3 Products(1)

mRNA Protein Name
NM_011517.2 NP_035647.2 synaptonemal complex protein 3
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
12759374 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
involved in chiasma assembly IDA
IDA: Inferred from direct assay
12004129 MGI
acts upstream of or within chiasma assembly IGI
IGI: Inferred from genetic interaction
22164254 MGI
involved in female meiosis chromosome segregation IDA
IDA: Inferred from direct assay
12004129 MGI
involved in female meiosis sister chromatid cohesion IDA
IDA: Inferred from direct assay
15870106 MGI
acts upstream of or within homologous chromosome pairing at meiosis IMP
IMP: Inferred from mutant phenotype
15870106 MGI
acts upstream of or within lateral element assembly IGI
IGI: Inferred from genetic interaction
22164254 MGI
acts upstream of or within meiotic DNA repair synthesis IGI
IGI: Inferred from genetic interaction
22164254 MGI
acts upstream of or within meiotic cell cycle IDA
IDA: Inferred from direct assay
12091911 MGI
acts upstream of or within mitotic cell cycle IDA
IDA: Inferred from direct assay
10809667 MGI
acts upstream of or within sperm DNA condensation IGI
IGI: Inferred from genetic interaction
22164254 MGI
acts upstream of or within spermatogenesis IGI
IGI: Inferred from genetic interaction
22164254 MGI
involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
10678170 MGI
involved in synaptonemal complex assembly IDA
IDA: Inferred from direct assay
10678170 MGI
acts upstream of or within synaptonemal complex assembly IGI
IGI: Inferred from genetic interaction
22164254 MGI
Cellular Component GO Annotation Evidence Reference Source
located in chromosome IDA
IDA: Inferred from direct assay
10794082 MGI
located in chromosome, centromeric region IDA
IDA: Inferred from direct assay
28380054 MGI
located in condensed chromosome IDA
IDA: Inferred from direct assay
10809667 MGI
located in condensed chromosome, centromeric region IDA
IDA: Inferred from direct assay
22854038 MGI
located in condensed nuclear chromosome IDA
IDA: Inferred from direct assay
18316482 MGI
located in female germ cell nucleus IDA
IDA: Inferred from direct assay
21621532 MGI
located in lateral element IDA
IDA: Inferred from direct assay
10678170 MGI
located in male germ cell nucleus IDA
IDA: Inferred from direct assay
17696610 MGI
located in synaptonemal complex IDA
IDA: Inferred from direct assay
12815066 MGI
located in transverse filament IDA
IDA: Inferred from direct assay
15870106 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

synaptonemal complex protein 3

SCP-3

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14072 SYCP3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21776 Sycp3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sycp3 NCBI NCBI:50511